Scleroderma systematica concurrent with neoplasm

Scleroderma with Nodular Scleroderma

BACKGROUND Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea. A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type. Treatment is challenging, and several treatments modalities have been reported with unsatisfactory results. MAIN OBSERVATIONS We present a case of systemic scleros...

When is scleroderma really scleroderma?

Scleroderma.

The prototypic autoimmune diseases involving skin (lupus, dermatomyositis) typically result in epithelial injury and autoantibodies to characteristic cellular antigens. Disease-specific autoantibodies are also found in scleroderma, but scleroderma is different from other cutaneous autoimmune diseases because epithelial injury does not occur. Multiple factors and combinations of factors (immune ...

Linear scleroderma with partial anonychia

Morphine inhibits the expression of antigenic markers for T-helper cells and also the respiratory burst of these cells.[6] This drug suppresses antibody production in response to the T cell-dependent antigens.[6] It also leads to elevated plasma levels of corticotropinreleasing hormone (CRH), adrenocorticotropic hormone (ACTH) and glucocorticoids.[6] Therefore, through suppression of the immune...

Chronic abdominal pain, appendiceal mucinous neoplasm, and concurrent intestinal endometriosis: a case report

UNLABELLED INTRODUCTION Although both appendiceal tumor and intestinal endometriosis have been reported as rare causes of abdominal pain, the coexistence of appendiceal mucinous neoplasm and ileal endometriosis has not previously been reported. CASE PRESENTATION A 41-year-old Japanese woman presented with a positive fecal occult blood test and a 3-year history of menstruation-related lower...